Bioactive Small Molecules
Cayman Chemical ANTIBODY ZL006 50mg
An nNOS/PSD-95 interaction inhibitor; inhibits NMDA-induced lactate dehydrogenase release (IC50 = 0.082 µM), as well as glutamate and glycine-induced, NMDA receptor-dependent production of NO, in primary mouse neurons; prevents ischemia-induced increases in nNOS-PSD-95 complex formation in cortices isolated from a mouse model of MCAO-induced ischemia-reperfusion injury; reduces infarct size and increases survival in the same model; suppresses mechanical and cold allodynia in a mouse model of paclitaxel-induced neuropathic pain
Cayman Chemical N N-DIphenthylurea 5mg
A bacterial metabolite with diverse biological activities; inhibits Streptomyces chitin synthase 1 (IC50 = 14 UG/ml); active against C. neoformans and R. solani (MIC = 50 UG/ml for both); enhances insulin-induced adipocyte differentiation in 3T3-L1 and C3H/10T1/2 cells at 30 and 100 µM
Medchemexpress LLC Mitochondria degrader-1 | 2241669-05-4 | 95.1% | 758.30 | 25 MG
Mitochondria degrader-1 is a potent compound engineered to induce the degradation of injured mitochondria through the autophagy mechanism. This degrader facilitates the removal of damaged mitochondria, making it a valuable tool for research in various disease areas.
- Valuable tool for research in various disease areas
- Applications span across studies related to neurodegenerative diseases, cancer, inflammatory conditions, age-related diseases, metabolic disorders, mitochondrial diseases, and Down's disease
Abcam TGR5 Receptor Agonist, TGR5 G-protein coupled receptor agonist, 5MG
MW 361.2 Da, Purity >99%. Potent, selective TGR5 G-protein coupled receptor agonist (pEC₅₀ = 6.8). Increases glucagon-like peptide-1 (GLP-1) secretion from primary intestinal cells. Cell-permeable. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical ANTIBODY9-HODE 1mg
A acemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid
Cayman Chemical ANTIBODY AcyclovIr 25mg
An antiviral guanosine analog; has antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1-63.1 μM); diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a virus-specific thymidine kinase; reduces viral titers in mice infected with the HSV-1 strain SC16
Cayman Chemical ANTIBODY ML-204 50mg
Selectively blocks TRPC4 channels (IC50s = 0.96 and 2.6 μM in fluorescent and electrophysiological assays, respectively)
Cayman Chemical ANTIBODY HesperIdIn 25g
A flavanone rutinoside found in citrus peels with antioxidant, anticancer, and estrogenic effects in in vitro and in vivo research models; increases the cytotoxicity of doxorubicin on MCF-7 and HeLa cancer cells; decreases serum and hepatic lipid concentrations and reduces osteoporosis in ovariectomized rats
Medchemexpress LLC HY-109091B 5mg Medchemexpress, Lanraplenib (succinate) CAS:1800047-00-0 Purity:>98%
Medchemexpress, HY-109091B 5mg Lanraplenib (succinate) CAS:1800047-00-0 Lanraplenib succinate (GS-9876 succinate) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib succinate (GS-9876 succinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans[3]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical LIfItegrastsodIum salt 5mg
An inhibitor of the LFA-1/ICAM-1 interaction; binds to LFA-1 and blocks the adhesion of Jurkat T cells or HuT 78 cells to ICAM-1 (IC50s = 2.98 and 9 nM, respectively) and inhibits secretion of various cytokines from these cells; increases tear production in dogs with idiopathic keratoconjunctivitis sicca; topical application inhibits LFA-1-dependent neutrophil recruitment to the eye in mouse models of contact lens-associated corneal inflammation induced by corneal abrasion and tobramycin-killed bacteria
Cayman Chemical CIprofIbrate-d6 5mg
An internal standard for the quantification of ciprofibrate by GC- or LC-MS
Medchemexpress LLC SENP2-IN-1 | 2986220-46-4 | C32H29N3O5S2 | 5 MG
SENP2-IN-1 (compound 77) is a selective SENP2 inhibitor. It exhibits inhibitory activities with IC₅₀ values of 1.3 μM for SENP1, 0.69 μM for SENP2, and 22.7 μM for SENP5. This compound is suitable for research related to cancer.
- Selective SENP2 inhibitor
- Exhibits inhibitory activities with IC₅₀ values of 1.3 μM for SENP1, 0.69 μM for SENP2, and 22.7 μM for SENP5
- Suitable for cancer research
- Applicable to digestive system disease, liver cancer, and digestive system cancer research
- Used in cancer targeted therapy, cancer metabolism, and metastasis research
Cayman Chemical ANTIBODY DeracoxIb 25mg
An NSAID and selective COX-2 inhibitor (IC50s = 0.63 and 23 μM for COX-2 and COX-1, respectively); increases weight bearing and decreases lameness and joint effusion in a canine model of urate crystal-induced intraarticular synovitis; induces less lesion formation in the gastric mucosa of healthy canines than aspirin at 1.5 mg/kg
eMolecules 488097-06-9 | VU 0650991 | Tocris Bioscience (Bio-Techne US)440.730 | C16H11ClF6N4O2 | 98.000 | Cn1c2NC(=NC(c2c(=O)n(C)c1=O)(C(F)(F)F)C(F)(F)F)c1ccc(Cl)cc1 | 10mg | 454171286
VU 0650991 | Tocris Bioscience (Bio-Techne US) | 488097-06-9440.730 | C16H11ClF6N4O2 | 98.000 | Cn1c2NC(=NC(c2c(=O)n(C)c1=O)(C(F)(F)F)C(F)(F)F)c1ccc(Cl)cc1 | 10mg | 454171286
Medchemexpress LLC CNTF Human 100ug
Recombinant human ciliary neurotrophic factor (CNTF) supplied lyophilized for research use. CNTF is a pluripotent cytokine in the IL-6 family that promotes survival, differentiation, and neurite outgrowth of central and peripheral neurons, including retinal photoreceptors. The protein is produced in E. coli, supplied with high purity, and formulated for stable storage and convenient reconstitution.
- Supports neuronal survival and differentiation.
- Protects retinal cone and rod photoreceptors.
- Produced in E. coli and supplied tag-free.
- Purity greater than 95% by reducing SDS-PAGE.
- Lyophilized formulation for stable storage.
- Recommended storage at -20°C; aliquot and store at -80°C for long term.